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Buy Sildenafil (Viagra) powder. Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women. It is taken by mouth or by injection into a vein. Onset is typically within twenty minutes and lasts for about two hours. Buy Sildenafil (Viagra) powder
Common side effects include headaches, heartburn, and flushed skin. Caution is advised in those with cardiovascular disease. Rare but serious side effects include a prolonged erection (priapism) that can lead to damage to the penis, vision problems, and hearing loss. Sildenafil should not be taken by people on nitrates such as nitroglycerin (glycerin trinitrate), as this may result in a serious drop in blood pressure. Sildenafil should not be taken within four hours of taking an alpha blocker.
Sildenafil acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. It requires sexual arousal to work. It also results in dilation of the blood vessels in the lungs. Buy Sildenafil (Viagra) powder
Pfizer originally discovered the medication in 1989 while looking for a treatment for heart-related chest pain. It was approved for medical use in the United States and in the European Union in 1998. In 2020, it was the 183rd most commonly prescribed medication in the United States, with more than 2 million prescriptions. It is available as a generic medication. In the United Kingdom, it is available over the counter. Most of the Active Pharmaceutical Ingredient (API) in Sildenafil, Sildenafil citrate, is produced in Pfizer’s Ringaskiddy complex, County Cork, which is Pfizer’s largest production facility outside of the United States. Buy Sildenafil (Viagra) powder
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Sildenafil is a member of the agents for pulmonary hypertension drug class and is commonly used for Erectile Dysfunction, Pulmonary Hypertension, and Sexual Dysfunction – SSRI Induced. Buy Sildenafil (Viagra) powder
Brand names for sildenafil include Viagra, and Revatio.
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|---|---|---|---|
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| Delivery Time: | Within 12hours After Payment | CAS Register Number: | 521-11-9 |
| Molecular Formula: | C20H32O2 | Molecular Weight: | 304.47 |
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Sildenafil CAS: 139755-83-2
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| Items | Standard | Results |
| Assay by HPLC: | 98% | 99.37% |
| Appearance: | White fine powder | Complies |
| Odor & taste: | Slight bitter | Complies |
| Mesh size: | 100% pass 80mesh | Complies |
| Solubility: | Soluble in water | Complies |
| Loss on drying: | ≤2.0% | 1.15% |
| Heavy metals PPM: | <30ppm | Complies |
| Microbiology: Total Plate Count: Yeast & Mold: E.Coli: S. Aureus: Salmonella: | <1000cfu/g <100cfu/g Negative Negative Negative | 800cfu/g 90cfu/g Complies Complies Complies |
| Conclusion: | Conform with USP 32 | |
During sexual stimulation, the penis non-adrenergic non-cholinergic neuronal nitric oxide synthase and vascular endothelial L-arginine catalyzed synthesis of nitric oxide, which activate guanylate cyclase to make cyclic monophosphate guanosine synthesis, thereby giving rise to smooth muscle relaxation of corpus cavernosum smooth muscle, and small arteries, cavernous blood into the penis, so that penile erection. Meanwhile cyclic guanosine monophosphate and by hydrolysis of phosphodiesterase.
Thus, in theory, both to improve the guanylate cyclase activity, or inhibiting phosphodiesterase activity, can increase the cGMP level, it helps penile corpus cavernosum smooth muscle and smooth muscle of small arteries relaxation. Viagra (sildenafil) is through inhibition of the hydrolytic activity of phosphodiesterase to increase cGMP levels without affecting cAMP, thereby increasing the sexual stimulation of nitric oxide synthase / cyclic guanosine monophosphate waterfall effect, so cavernous smooth muscle relaxation, to achieve the purpose of treatment of erectile dysfunction. Buy Sildenafil (Viagra) powder
For most patients, the recommended dose is 50mg, in about 1 hour before sexual activity taking; but any time before sexual activity within 0.5 to 4 hours can be taken. Based on the efficacy and tolerability, the dose can be increased to 100 mg (the maximum recommended dose) or decreased to 25 mg. Maximum daily doses of 1. Buy Sildenafil (Viagra) powder
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