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Buy Spironolactone steroid powder. Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It is also used in the treatment of high blood pressure, low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women, and as a part of transgender hormone therapy in transfeminine people. Spironolactone is taken by mouth. Buy Spironolactone steroid powder
Common side effects include electrolyte abnormalities, particularly high blood potassium, nausea, vomiting, headache, rashes, and a decreased desire for sex. In those with liver or kidney problems, extra care should be taken.Spironolactone has not been well studied in pregnancy and should not be used to treat high blood pressure of pregnancy. It is a steroid that blocks the effects of the hormones aldosterone and testosterone and has some estrogen-like effects. Spironolactone belongs to a class of medications known as potassium-sparing diuretics. Buy Spironolactone steroid powder
Spironolactone was discovered in 1957, and was introduced in 1959.It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication. In 2020, it was the 51st most commonly prescribed medication in the United States, with more than 13 million prescriptions. Buy Spironolactone steroid powder
CAS: | 52-01-7 | MF: | C24H32O4S |
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MW: | 416.57 | EINECS: | 200-133-6 |
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API Anabolic Androgenic Steroids, Steroids Spironolactone, Spironolactone CAS 52-01-7 |
Anabolic Androgenic Steroids Spironolactone CAS 52-01-7 Pharmaceutical API
Spironolactone
CAS: 52-01-7
MF: C24H32O4S
MW: 416.57
EINECS: 200-133-6
ITEMS SPECIFICATION
Appearance almoste white crystalline powder
Melting point 198-209°C
Specific rotation between -33°And- 37°
Indentificaftion meet the requirements
Relate substances sum of impurities
(except canrenone) ≤ 1.0%
Canrenone ≤ 1.0%
Sum of impurities+canrenone ≤ 1.0%
Chromium ≤ 50ppm
Loss on drying ≤ 0.5%
Sulphated ash ≤ 0.1%
Heavy Metal ≤ 0.002%
Limit of mercapto compounds Conform
Ordinary impurities Conform
Assay (on the dried basis) 97%~102.0%
Chemical Properties White to Off White Solid
Usage It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia
Usage diuretic, aldosterone antagonist
Biological Activity Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis. Buy Spironolactone steroid powder
Spironolactone Specification:
Test Items | Specification | Test Results |
Appearance | Almost white crystalline powder | Almost white crystalline powder |
Identification | Meet the requirements | Meet the requirements |
Melting range | 198℃~209℃
Between 198℃ and 209℃ |
205.0℃~207.0℃ |
Specific rotation | -33°~-37°
Between -33° and -37° |
-35° |
Loss on drying | ≤0.5%
Not more than 0.5% |
0.2% |
Limit of mercapto compounds | Meet the requirements | Meet the requirements |
Ordinary impurities | Meet the requirements | Meet the requirements |
Organic volatile impurities | Meet the requirements | Meet the requirements |
Assay(on the dried basis) | 97.0%~103.0%(C24H32O4S)
Between 97.0% and 103.0% |
98.99% |
Conclusion | Meet the requirements of USP29 |
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