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Clomifene was approved for medical use in the United States in 1967. It is on the World Health Organization’s List of Essential Medicines, under the category “Ovulation inducers” (Complementary List). Its introduction began the era of assisted reproductive technology. Buy Clomifene (clomiphene) powder
Clomifene (particularly the purified enclomiphene isomer) has also been found to have a powerful ability to boost or restore testosterone levels in hypogonadal men. Buy Clomifene (clomiphene) powder
| Brand Name: | Clomiphene | CAS: | 50-41-9 |
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| CAS Number | 50-41-9 |
| Synonyms | Clomifene Omifin NSC 35770 |
| Molecular Formula | C26H28ClNO • C6H8O7 |
| Formula Weight | 598.1 |
| Purity | ≥98% |
| Formulation | A crystalline solid |
| λmax | 205, 236, 294 nm |
| Appearance | Clomiphene citrate is a white to pale yellow, essentially odorless, crystalline powder. It is freely soluble in methanol; soluble in ethanol; slightly soluble in acetone, water, and chloroform; and insoluble in ether. |
| Usage | Clomiphene is a selective estrogen receptor modulator that impairs the activation of estrogen receptors. Clomiphene enhances the release of gonadotropin-releasing hormone, stimulating the release of follicle-stimulating hormone and luteinizing hormone, culminating in ovulation. Buy Clomifene (clomiphene) powder |
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When a steroid user runs a steroid cycle their HPTA becomes suppressed; as a result, their bodies LH and FSH drop to almost zero (0) and their body stops producing testosterone. Their testicles typically will shrink as the body realizes there are too many hormones present and it’s not necessary to produce more. So, when you come off a cycle it’s important to run a PCT (post cycle therapy) to help recover the body’s HPTA. Buy Clomifene (clomiphene) powder
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Clomiphene citrate is capable of interacting with estrogen-receptor-containing tissues, including the hypothalamus, pituitary, ovary, endometrium, vagina, and cervix. It may compete with estrogen for estrogen-receptor-binding sites and may delay replenishment of intracellular estrogen receptors. Clomiphene citrate initiates a series of endocrine events culminating in a preovulatory gonadotropin surge and subsequent follicular rupture. The first endocrine event in response to a course of clomiphene therapy is an increase in the release of pituitary gonadotropins. This initiates steroidogenesis and folliculogenesis, resulting in growth of the ovarian follicle and an increase in the circulating level of estradiol. Following ovulation, plasma progesterone and estradiol rise and fall as they would in a normal ovulatory cycle. Buy Clomifene (clomiphene) powder
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