USP Anastrozole/ Arimidex​​​ CAS 120511-73-1 Antiestrogen Anti-Cancer 99.8% Steroid Powder

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Product Name: Anastrozole/ Arimidex

CAS: 120511-73-1
MF: C17H19N5
MW: 293.37

Purity: 99.8%

Standard: USP32
Appearance: White crystalline powder

Categories: Antineoplastic; All Inhibitors; Anti-neoplastic; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Anastrozole; API

Usage: Anastrozole / Arimidex is not a steroid, but it is used during very high androgenic steroids such as Dianabol and testosterone where estrogen levels need to be watched because of gynecomastia and water retention purposes. Buy Arimidex (Anastrozole) powder

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Anastrozole/ Arimidex​​​ Quality Test Report(COA):

Description and Applications:

Anastrozole (INN) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites. Anastrozole works by inhibiting the synthesis of estrogen. The patent on Arimidex by AstraZeneca expired June 2010.

It is on the World Health Organization’s List of Essential Medicines, a list of the most important medications needed in a basic health system. Buy Arimidex (Anastrozole) powder

Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer. Buy Arimidex (Anastrozole) powder

Arimidex is the aromatase inhibitor of choice. Arimidex ‘s mechanism of action – blocking conversion of aromatizable steroids to estrogen – is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid)  (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others. Buy Arimidex (Anastrozole) powder

The ATAC trial was an international randomised controlled trial of 9366 women with localized breast cancer who received either anastrozole, tamoxifen, or both for five years, followed by five years of follow-up. After more than 5 years the group that received anastrozole had significantly better clinical results than the tamoxifen group. The trial suggested that anastrozole is the preferred medical therapy for postmenopausal women with localized breast cancer, which is estrogen receptor (ER) positive. Another study found that the risk of recurrence was reduced 40%, but was associated with an increased risk of bone fractures. The study concluded that ER positive patients benefited from switching from tamoxifen to anastrozole in patients who have completed 2 years’ adjuvant tamoxifen. A more recent trial found that anastrozole significantly reduced the incidence of breast cancer in postmenopausal women relative to placebo, and while there were side effects related to estrogen deprivation observed, the researchers concluded that this was probably not related to the treatment. Lead author Jack Cuzick was quoted by the BBC as saying, “This class of drugs is more effective than previous drugs such as tamoxifen and crucially, it has fewer side effects,” adding that he thought there was now enough evidence to support offering the drug. Buy Arimidex (Anastrozole) powder

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